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United States Post Office
401 Church St, O Fallon, MO 63366
This United States Post Office serves the 63366 Zip Code portion of O'Fallon. It is a full service post office butMore you can skip the postal clerk by using one of the two self-service machines in the lobby. It also rents  PO Boxes  with 24-hour access. Outside there is a drive through lane with mail boxes to drop letters in.  
The Mail Depot
3023 Highway K, O Fallon, MO 63368
Mail Depot can help you ship items via UPS, take your passport photos and provide you with shipping supplies. Going hereMore is often quicker than visiting the post office. The staff is very friendly and will provide shipping price quotes.
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